Glenmark Ondansetron 4mg Disintegrating Tablets

Product Overview:

Ondansetron 4mg Tablets are an effective antiemetic medication designed to prevent nausea and vomiting caused by certain medical treatments. These treatments include chemotherapy, radiation therapy, and surgery. Ondansetron belongs to a class of medications known as serotonin 5-HT3 receptor antagonists, which work by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

Key Features:

1. Active Ingredient:

• Each tablet contains 4mg of Ondansetron, a potent serotonin 5-HT3 receptor antagonist known for its efficacy in controlling nausea and vomiting.

• Ondansetron 4mg Tablets are widely used in clinical settings to prevent and manage nausea and vomiting induced by chemotherapy, radiation therapy, and postoperative recovery. They are particularly beneficial in reducing the discomfort and complications associated with these conditions.

• The tablets are easy to administer and can be taken with or without food. This makes them a convenient option for patients undergoing treatment who need reliable and quick relief from nausea.

• Ondansetron works quickly, often within 30 minutes of administration, making it an ideal choice for both acute and preventative management of nausea and vomiting.

Indications: Ondansetron 4mg Tablets are indicated for:

• The prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy, including cisplatin ≥50mg/m².
• The prevention of nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy.
• The prevention of postoperative nausea and vomiting.
• The prevention of nausea and vomiting associated with radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen.

Contraindications and Precautions:

• Contraindications: Ondansetron is contraindicated in patients with known hypersensitivity to the drug or any of its components.
• Precautions: Use with caution in patients with hepatic impairment, as dosage adjustments may be necessary. Monitor for signs of serotonin syndrome, especially when Ondansetron is used in combination with other serotonergic drugs.

Side Effects: Common side effects may include:

• Headache
• Fatigue
• Constipation
• Diarrhea

Serious but rare side effects may include:

• Hypersensitivity reactions, including anaphylaxis
• ECG changes, including QT prolongation
• Serotonin syndrome

Storage and Handling:

• Store Ondansetron 4mg Tablets at room temperature, away from moisture and heat. Keep the tablets in their original packaging until ready to use to protect them from light and humidity.