Esmolol Hcl 100mg | 10mL Injectable SDV

Overview:

Esmolol HCl is a short-acting beta-blocker used to manage acute tachycardia and hypertension. It is especially effective in situations requiring rapid but brief beta-adrenergic blockade. This product comes in a 100mg/10mL single-dose vial (SDV), ensuring precise dosing and ease of administration for healthcare professionals.

Key Features:

• Rapid Onset and Short Duration: Esmolol HCl is known for its quick onset of action and short duration, making it ideal for acute settings where immediate but temporary beta-blockade is required.
• Single-Dose Vial (SDV): The 10mL vial format ensures accurate dosing and reduces the risk of contamination, promoting safe and efficient patient care.
• Beta-1 Selective Adrenergic Blocker: Esmolol HCl selectively targets beta-1 receptors, providing effective heart rate control with minimal impact on beta-2 receptors, reducing the risk of bronchoconstriction.

Indications:

• Supraventricular Tachycardia (SVT): Effective in controlling rapid heart rates associated with SVT.
• Perioperative Tachycardia and Hypertension: Used to manage heart rate and blood pressure during surgical procedures.
• Hypertensive Emergencies: Provides rapid blood pressure reduction in emergency situations.

Dosage and Administration:

• Dosage: The typical initial dose is a 500 mcg/kg bolus over 1 minute, followed by a maintenance infusion of 50-200 mcg/kg/min. Dosage adjustments should be based on the patient's response and clinical condition.
• Administration: Administered intravenously, ensuring immediate availability of the drug in the bloodstream for quick therapeutic action.

Contraindications and Precautions:

• Contraindications: Patients with known hypersensitivity to esmolol or any component of the formulation, severe bradycardia, heart block greater than first degree, cardiogenic shock, and overt heart failure.
• Precautions: Caution should be exercised in patients with reactive airway diseases, diabetes, and impaired renal function. Continuous monitoring of heart rate and blood pressure is recommended during administration.

Side Effects:

• Common Side Effects: Hypotension, bradycardia, dizziness, nausea, and fatigue.
• Serious Side Effects: Severe hypotension, heart failure, and bronchospasm in susceptible individuals.

Storage and Handling:

• Storage: Store at controlled room temperature, 20° to 25°C (68° to 77°F). Protect from light and freezing.
• Handling: Use aseptic technique when handling and administering the medication to maintain sterility and prevent contamination.