Flumazenil 0.1mg | 5mL Injectable MDV

Product Overview:

Flumazenil 0.1mg/mL Injectable MDV (Multi-Dose Vial) is a benzodiazepine antagonist that is used to reverse the sedative effects of benzodiazepines. It is administered intravenously and is particularly useful in situations where rapid reversal of benzodiazepine sedation or overdose is required. The multi-dose vial offers convenience and flexibility for healthcare providers, allowing for multiple administrations from a single vial.

Key Features:

1. Concentration and Volume:

• Each vial contains 5mL of solution with a concentration of 0.1mg of flumazenil per milliliter. This allows for precise dosing and easy titration based on patient needs.

• Flumazenil is specifically indicated for the reversal of the sedative effects of benzodiazepines used in anesthesia, diagnostic, or therapeutic procedures. It can also be used in cases of benzodiazepine overdose.

• The intravenous administration of flumazenil provides a rapid onset of action, typically within 1 to 2 minutes, making it ideal for emergency situations where immediate intervention is required.

• The product is packaged in a multi-dose vial, allowing for multiple doses to be drawn from a single vial. This reduces waste and ensures that the medication is available for repeated use as needed.

• Flumazenil has a favorable safety profile when used as directed. It effectively reverses sedation without causing significant adverse effects in most patients.

Contraindications and Precautions:

• Contraindications: Flumazenil is contraindicated in patients with known hypersensitivity to flumazenil or any of the excipients in the formulation.
• Precautions: Caution is advised in patients with epilepsy or severe hepatic impairment, as flumazenil may precipitate seizures in these populations. Use with caution in patients with a history of panic disorder or anxiety, as it may induce withdrawal symptoms.

Side Effects: Potential side effects may include, but are not limited to:

• Nausea and vomiting
• Dizziness
• Agitation or anxiety
• Seizures (particularly in patients with long-term benzodiazepine use or overdose)

Storage and Handling:

• Store at controlled room temperature, away from light and moisture.
• Once the vial is opened, it should be used within the time frame recommended by the manufacturer to ensure sterility and potency.